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  • Writer's pictureWomen's Cancer Research Foundation


Incidence and Risk Factors of Ovarian Cancer and Breast Cancer Following Prophylactic Surgery: A Retrospective Cohort Study

Newport Beach, CA – April 13, 2020 – Women’s Cancer Research Foundation (WCRF) has published a paper about 231 patients with BRCA 1/2 genetic mutations who underwent prophylactic removal of their fallopian tubes and ovaries.  Based on known BRCA 1/2 data, 78 of these patients would have developed ovarian cancer. None of the patients did. 

One patient had an unexpected occult fallopian tube cancer, and we expect her to have been cured by the surgery.  Five patients did develop nonovarian cancer (primary peritoneal cancer). This is consistent with other studies of BRCA 1 / 2 gene-positive patients.

Dr. Micha noted, “This is great that 78 patients were prevented from getting ovarian cancer with a simple laparoscopic/robotic surgery.”  Dr. Micha also added, “We thank Joan and Len Rullo for supporting this study in honor of Joan’s mother, Elizabeth Johnson.”

For the Abstract and Full Journal Article please visit:

About Women’s Cancer Research Foundation The Women’s Cancer Research Foundation (WCRF) is one of Southern California’s and the nation’s most active research organizations for female cancers. We are dedicated to serving the interests of patients, families, and friends affected by women’s cancers. WCRF partners with physician-scientists nationally to make differences in women’s lives by offering hope, strength, and progress.

John Paul Micha, M.D.  Chairman, Women’s Cancer Research Foundation Women’s Cancer Research Foundation (WCRF) 351 Hospital Road, Suite 506 Newport Beach, CA 92663 PH: (949) 642-5165

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