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  • Writer's pictureWomen's Cancer Research Foundation

Long-term Pelvic Fracture and Overall Mortality Risk After Pelvic Cancer Radiation

Updated: Jan 12


Cancer Research

The association between pelvic radiation for the treatment of gynecologic cancers and subsequent risk for pelvic fractures has not been previously examined. In a study conducted from 1993 to 1998, 135,743 women, aged 50 to 79 years, were eligible for study inclusion. The outcomes included pelvic cancer diagnosis, pelvic fracture occurrence, and mortality.


Postmenopausal women with pelvic cancer, especially those receiving pelvic radiation, are at higher risk for developing a pelvic fracture risk and have higher mortality rates.

After 17.7 years, 4451 pelvic cancers, 10,139 pelvic fractures, and 33,040 deaths occurred. Women with a pelvic cancer who were treated with pelvic radiation, compared with women with a pelvic cancer who were not treated with pelvic radiation, had a higher incidence of pelvic fractures and higher overall mortality. Postmenopausal women with pelvic cancer, especially those receiving pelvic radiation, are at higher risk for developing a pelvic fracture risk and have higher mortality rates. Consequently, additional study of interventions that address pelvic fracture prevention is indicated for pelvic cancer survivors.


About Women’s Cancer Research Foundation


The Women’s Cancer Research Foundation (WCRF) is one of the most active research organizations in the nation. We are dedicated to studying and evaluating novel treatments for women afflicted with breast, ovarian, endometrial, and cervical cancers. The WCRF persistently endeavors to make a difference in women’s lives by offering them hope, strength, and progress.



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