Research Context: The Rise in Early-Onset Cancer in the US Population - More Apparent Than Real
- Women's Cancer Research Foundation

- 12 minutes ago
- 1 min read

Rising rates of early-onset cancer have generated substantial and hence, clinical guidelines have shifted to recommend earlier screening for some cancers. Nevertheless, we are uncertain whether rising rates represent an accurate true increase in cancer occurrence.
In a recent study, researchers examined 8 cancers with the fastest-rising incidence (thyroid, anus, kidney, small intestine, colorectum, endometrium, pancreas, and myeloma) and evaluated their independent impact on mortality rates. Colorectal and endometrial cancer showed a slight rise in mortality, whereas the other cancers remained stable or had declining mortality rates.
Incidental detection or earlier diagnosis may explain the trends but ultimately, the rise in early-onset cancer incidence does not consistently signal a rise in the occurrence of clinically meaningful cancer.
About Women’s Cancer Research Foundation:
The Women’s Cancer Research Foundation (WCRF) is one of the most active research organizations in the nation. We are dedicated to studying and evaluating novel treatments for women afflicted with breast, ovarian, endometrial, and cervical cancers. The WCRF persistently endeavors to make a difference in women’s lives by offering them hope, strength, and progress.










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